In the early 1960s a Belgian advertising dropout, Guy Peelaert, created his childish and witty comic The Adventures of Jodelle. Fantagraphics recently released a newly-translated collection of the comic, featuring an in-depth look at the artist who managed "to transform a previously save medium into something exciting and dangerous."
One of our favorites, It's Nice That, explains it nicely(ha!):
"The Adventures of Jodelle was a comic book unlike anything the world had ever seen. Gone were the spandex-clad superheroes and simple, good vs evil, narrative structures upon which so many children had squandered their free time and in replacement the very first adult-themed graphic novel, complete with ample chests, Roman setting and an allegorical spy narrative."